Wuhan Yuancheng Gongchuang Technology Co., Ltd.

Lidocaine, Xylocaine, Benzocaine manufacturer / supplier in China, offering Amino Amide Type Local Anesthetic Xylocaine Lidocaine, Adrenalone Hydrochloride, Dl-Adrenalin, Epinephrine Bitartrate, Isoprenaline Hydrochloride, 99% Purity Estradiol with Safe Shipping and so on.

Supplier Homepage Product List Pharmaceutical Intermediates Amino Amide Type Local Anesthetic Xylocaine Lidocaine

Amino Amide Type Local Anesthetic Xylocaine Lidocaine

FOB Price:US $30 - 35 / kg
Purchase Qty. (kg) FOB Price
1-24 US $35 / kg
25-99 US $32 / kg
100+ US $30 / kg
Get Latest Price
Min. Order: 1 kg
Production Capacity: 500000 T/Month
Transport Package: 25kg/Drum, 1kg/Bag
Payment Terms: T/T, Money Gram, Western Union

Basic Info.

Model NO.:137-58-6 Lidocaine
Function:Keeping Health and Promoting Growth
Product Name:Lidocaine
Catalog:Local Anesthetic
Class:Medicine Materials
Specification:Enterprise Standard/Pharma Grade
Origin:Wuhan, China
HS Code:2937290000

Product Description

1. Basic Information:

Product NameLidocaine
SynonymXylocaine, 2-(diethylamino)-N-(2, 6-dimethylphenyl)acetamide
Molecular Structure
Quality StandardsEnterprise Standard/Pharma Grade
AppearanceWhite powder

Place of OriginChina
Brand NameSMQ
CertificationISO9001, ISO14000, KOSHER
Model Number137-58-6
Ref. PriceUSD 30/kg
Packaging Details25kg/Drum, 1kg/bag
Delivery Time1-2 days
Payment TermsT/T, Western union, Money gram
Supply Ability500000 T/Month

2. Quick View:
Lidocaine (INN, BAN) xylocaine, or lignocaine (AAN, former BAN) is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.

3. History:
Lidocaine, the first amino amide–type local anesthetic, was first synthesized under the name 'xylocaine' by Swedish chemist Nils Lö Fgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself. It was first marketed in 1949.

4. Pharmacodynamics:
(1) Anaesthesia
Lidocaine alters signal conduction in neurons by blocking the fast voltage-gated Na+ channels in the neuronal cell membrane responsible for signal propagation. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain, but by stopping them before they begin. Careful titration allows for a high degree of selectivity in the blockage of sensory neurons, whereas higher concentrations also affect other modalities of neuron signaling.
(2) Antiarrhythmic
The same principle applies for this drug's actions in the heart. Blocking sodium channels in the conduction system, as well as the muscle cells of the heart, raises the depolarization threshold, making the heart less likely to initiate or conduct early action potentials that may cause an arrhythmia.
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Wuhan Yuancheng Gongchuang Technology Co., Ltd.

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