Nolvadex Tamoxifen Citrate Anti Estrogen Steroids CAS 54965-24-1
|Product Name||Tamoxifen Citrate|
|Alias||Nolvadex; TAM,Tamoxifen citrat kessar; noltam; tamofen|
|Packing||foil bag or tin.|
|Boiling Point||482.3°C at 760 mmHg|
|Storage||Shading , confined preservation|
|Usage||anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases;It is used as a first line defense against breast cancer.|
Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties.
Nolvadex is an estrogen agonist in the liver, capable of activating the estrogen receptor and mimicking the actions of this sex hormone in this region of the body. As such it can have a markedly positive impact on HDL (good) cholesterol values, as does estrogen. Tamoxifen is currently used for the treatment of both early and advanced ER+ (estrogen receptor positive) breast cancer in pre- and post-menopausal women. Additionally, it is the most common hormone treatment for male breast cancer. It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease. It has been further approved for the reduction of contralateral (in the opposite breast) cancer.
Nolvadex or Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia. The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex.
Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure.
It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not strongest available remedy. We now have the drugs Arimidex, Femara, and Aromasin available to us, which notably prevents estrogen from being manufactured in the first place. Altering the effect of estrogen in the female body can cause a level of discomfort, so anti-estrogens are most bearable when used after the point of menopause. Since Nolvadex is milder in comparison, it is more widely applicable and usually the first treatment option
Few people will ever need more than 40mg per day and most will find that ending with a lower dose of 20mg per day is just about perfect. For the healthy adult male a good Nolvadex post cycle will run for approximately 4-6 weeks in total duration; 4 weeks should be the standard with 1-2 additional weeks being added if necessary. In most cases the additional weeks will only be needed if the anabolic steroid cycle was strong, was extended and of a high suppressive nature.
Post Cycle Therapy (PCT):
When a steroid user runs a cycle their HPTA becomes suppressed; as a result, their bodies LH and FSH drop to almost zero (0) and their body stops producing testosterone. Their testicles typically will shrink as the body realizes there are too many hormones present and it's not necessary to produce more. So, when you come off a cycle it's important to run a PCT (post cycle therapy) to help recover the body's HPTA.
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