Wuhan Yuancheng Gongchuang Technology Co., Ltd.

Gabapentin Hcl, Neurontin, Gabapentin manufacturer / supplier in China, offering Gabapentin HCl Anticonvulsant and Analgesic Drug Gabapentin Hydrochloride, Adrenalone Hydrochloride, Dl-Adrenalin, Epinephrine Bitartrate, Isoprenaline Hydrochloride, 99% Purity Estradiol with Safe Shipping and so on.

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Gabapentin HCl Anticonvulsant and Analgesic Drug Gabapentin Hydrochloride

FOB Price:US $45 - 50 / kg
Purchase Qty. (kg) FOB Price
1-24 US $50 / kg
25-99 US $47 / kg
100+ US $45 / kg
Get Latest Price
Min. Order: 1 kg
Production Capacity: 500000 T/Month
Transport Package: 25kg/Drum, 1kg/Bag
Payment Terms: T/T, Money Gram, Western Union

Basic Info.

Model NO.:60142-96-3 Gabapentin Hydrochloride
Function:Keeping Health and Promoting Growth
Product Name:Gabapentin Hydrochloride
Synonym:Neurontin, Fanatrex
Catalog:Anticonvulsant and Analgesic
Class:Medicine Materials
Specification:Enterprise Standard/Pharma Grade
Origin:Wuhan, China
HS Code:2937290000

Product Description

1. Basic Information:

Product NameGabapentin Hydrochloride
SynonymGabapentin, Neurontin, Fanatrex, Gabarone, Gralise, Nupentin, Neogab, GOE-3450, 2-[1-(aminomethyl)cyclohexyl]acetic acid
Molecular Structure
Quality StandardsEnterprise Standard/Pharma Grade
AppearanceWhite powder

Place of OriginChina
Brand NameSMQ
CertificationISO9001, ISO14000, KOSHER
Model Number60142-96-3
Ref. PriceUSD 45/kg
Packaging Details25kg/Drum, 1kg/bag
Delivery Time1-2 days
Payment TermsT/T, Western union, Money gram
Supply Ability500000 T/Month
2. Quick View:
(1) Gabapentin (Neurontin) is an anticonvulsant and analgesic drug. It was originally developed to treat epilepsy, and is currently also used to relieve neuropathic pain. It is recommended as a first line agent for the treatment of neuropathic pain arising from diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain.
(2) Gabapentin is also commonly prescribed for many off-label uses, such as treatment of restless leg syndrome, anxiety disorders, insomnia, and bipolar disorder. There are, however, concerns regarding the quality of the trials conducted and evidence for some such uses, especially in the case of its use as a mood stabilizer in bipolar disorder.
(3) Two related drugs, pregabalin and a prodrug form called gabapentin enacarbil, are available.

3. Medical uses:
Gabapentin is used primarily to treat seizures and neuropathic pain. There are, however, concerns regarding the quality of the research on its use to treat migraines, bipolar disorder, and pain.

4. Pharmacology:
(1) Gabapentin was initially synthesized to mimic the chemical structure of the neurotransmitter gamma-aminobutyric acid (GABA), but is believed to act on different brain receptors.

(2) Some of its activity may involve interaction with voltage-gated calcium channels. Gabapentin binds to the α 2δ Subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system. Another possible mechanism of action is that gabapentin halts the formation of new synapses.

5. Mechanism of action:
(1) The mechanism of the anticonvulsant action of gabapentin has not been fully described. Though similar in structure to the endogenous neurotransmitter GABA, gabapentin has not been shown to bind to GABA receptors at concentrations at or below 1000 µ M. Gabapentin modulates the action of glutamate decarboxylase (GAD) and branched chain aminotransferase (BCAT), two enzymes involved in GABA biosynthesis. In human and rat studies, gabapentin was found to increase GABA biosynthesis, and to increase non-synaptic GABA neurotransmission in vitro.

(2) Gabapentin (0.01-100 µ M) has not been shown to interact with the sodium or L-type calcium ion channels targeted by the conventional anticonvulsant drugs phenytoin, carbamazepine and sodium valproate. Other neurophysiological findings indicate that gabapentin does not interact with glutamate, glycine, or NMDA receptors, further distinguishing its anticonvulsant mechanism from that of common antiepileptic medications.
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Wuhan Yuancheng Gongchuang Technology Co., Ltd.

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