Wuhan Yuancheng Gongchuang Technology Co., Ltd.

GLP-1glucagon-Relatedpeptide, Polypeptide Hormones, Weight Loss manufacturer / supplier in China, offering Polypeptide Hormones 7-37-Glucagon-Likepeptide I High Quality, Steroids Injections Testosterone Propionate for Muscle Building, Highest Quality 99.5% Purity 2-Methyl-1-Butanol CAS: 137-32-6 and so on.

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Polypeptide Hormones 7-37-Glucagon-Likepeptide I High Quality

FOB Price:US $1 - 2 / mg
Purchase Qty. (mg) FOB Price
10-99 US $2 / mg
100-999 US $1.5 / mg
1,000+ US $1 / mg
Get Latest Price
Min. Order: 10 mg
Production Capacity: 5000g/Month
Transport Package: 2mg/Vial or as Your Request
Payment Terms: T/T

Basic Info.

Model NO.:106612-94-6
Type:Pharmaceutical Intermediates
Appearance:Powder
Quality:Medical Grade
Colour:White
Alias:7-37-Glucagon-Likepeptide I (Human)
CAS No:106612-94-6
M.F:C151h228n40o47
M.W:3355.74
Purity (HPLC):98.0%
Port:Hongkong, Shenzhen
Trademark:YC STEROID
Specification:SGS
Origin:Wuhan, China
HS Code:3001200020

Product Description

98% Polypeptide Hormones GLP-1 CAS 106612-94-6 Glucagon-Relatedpeptide 1 For The Treatment of Type 2 Diabetes Mellitus



1.Quick Detail:
GLP-1 (7-37) Acetate
Sequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Alias : 7-37-Glucagon-likepeptide I (human);Glucagon-relatedpeptide 1 (Rana catesbeiana),3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine-
Cas No.: 106612-94-6
Molecular Formula: C151H228N40O47
Molecular Weight: 3355.74
Purity (HPLC): 98.0%
Appearance: White powder
Single Impurity (HPLC): 1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): 80% (by %N)
Water Content (Karl Fischer): 6.0%
Acetate Content (HPIC): 15.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Manufacturer :SUPER STEROIDS
Delivery time : within 18 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage : GLP-1 can obviously improve the blood glucose in type 2 diabetes animal models or patients through a variety of mechanisms, which promote the regeneration and repair of islet beta cells, increase the number of beta cells is particularly significant role, provides a very good prospect for the treatment of type 2 diabetes mellitus.



2.Description:
Glucagon like peptide -1 (GLP-1) is a brain gut peptides secretion ileal endocrine cells, at present mainly as a target for type 2 diabetes drug action. Because GLP-1 can reduce the inhibition of gastric emptying, intestinal peristalsis, thus helps to control food intake, weight loss. Prospective placebo in 19 cases of obese patients in control, random, double-blind, crossover trial, GLP-1 subcutaneous injection can increase the patients with postprandial satiety, and make each meal diet weight average reduction of 15%. But because GLP-1 is a polypeptide, cannot be administered orally is a major shortcoming.
GLP-1 consists of proglucagon gene expression in pancreatic alpha cells, the main product, expression of proglucagon gene is glucagon, and in the intestinal mucosa of L cells, prohormone converting enzyme (PC1) the proglucagon peptide sequence in the carboxyl end shear, i.e. GLP-1. GLP-1 has 2 kinds of biological active forms, respectively GLP-1 (7-37) and GLP-1 (7-36) amide, both of which only one amino acid sequences different, cyclic activated about 80% GLP-1 from the GLP-1 (7-36 [1,2]) amide.



3.Application:
Effect of GLP-1 GLP-1 can protect beta cells can act on the pancreatic beta cells, promote the synthesis of insulin, insulin gene transcription and secretion and can stimulate the proliferation and differentiation of islet beta cells, inhibit the apoptosis of pancreatic beta cells, increase the number of beta cell of islet [2-5]. In addition, GLP-1 also can be applied to the pancreatic alpha cells, strongly inhibit the release of glucagon, and act on the islet delta cells, promote the secretion of somatostatin, somatostatin cells and can be used as a paracrine hormone involved in the inhibition of glucagon.
GLP-1 with glucose concentration dependent hypoglycemic effect, i.e. only rise in glucose levels under the condition of GLP-1, only play a hypoglycemic effect, but in normal blood sugar levels, caused no further decrease. The glucose concentration dependence of the GLP-1 is its hypoglycemic properties of clinical application safety of foundation and security, thereby avoiding people may cause severe hypoglycemia in patients with existing drug treatment for diabetes and scheme of worry.
In addition, GLP-1 also has many other biological characteristics and functions, for example, GLP-1 might play a lipid-lowering, antihypertensive effect, so as to have a protective effect on the cardiovascular system; it can also by acting on central reinforcement learning and memory function, protect the nerve.



4.Specification :

Product name
GLP-1 (7-37) Acetate
AppearanceWhite Powder
Assay98%
Molecular formulaC151H228N40O47
Molecular weight3355.74
Package2mg/vial or as your request
ShippingFast and secure shipping by DHL,EMS,UPS,TNT, FedEx..
Shipping leading timeWithin 18 hours after receiving the payment
Payment TermsWestern Union, Money Gram , T/T, PayPal
PriceNegotiable



Competitive Advantage:

1. Rich experience.
Delivery area:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

2. Great quality, purity and favourable.

3. Discreet delivery.

4. Good after-sales service.
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