Nature Procaine CAS: 59-46-1 Powder for Local Intravenous Anesthesia
·Synonyms:2- (Diethylamino) ethyl 4-aminobenzoate; 2- (diethylamino) ethylp-aminobenzoate; 2-diethylaminoethylester-2 -diethylaminoethylp-aminobenzoate; 4-Aminobenzoic acid diethylaminoethyl ester
·Appearance: White crystalline powder
·Procaine is a local anesthetic. Clinical commonly used in its hydrochloride, also known as "Nu Fu card." White crystalline or crystalline powder, soluble in water. Toxicity is lower than cocaine. Injection of trace adrenaline, can extend the role of time. For infiltration anesthesia, spinal anesthesia, "closed therapy" and so on. In addition to excessive medication caused by the central nervous system and cardiovascular system response, occasionally allergic reactions, medication should be used before the skin allergy test. Its metabolites p-aminobenzoic acid (PABA) can reduce the antibacterial effect of sulfonamides.
·Less toxic, is one of the commonly used local anesthetic. The drug is a short-acting ester local anesthetic, low lipophilicity, weak penetration of the mucosa. Generally not used for surface anesthesia, often local injection for infiltration anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia. Injection 1-3min after administration, can be maintained for 30-45min, plus adrenaline after the maintenance time can be extended by 20%. Procaine in the plasma can be esterase hydrolysis, into p-aminobenzoic acid (PABA) and diethylamino ethanol, the former can resist the anti-bacterial effect of sulfonamides, it should avoid the same application with sulfa drugs. Procaine can also be used to partially block the site of injury. Excessive use can cause central nervous system and cardiovascular response. Sometimes can cause allergic reactions, it should do before the skin allergy test, but the skin test can still occur allergic reactions. Allergic to the drug can be replaced with chloroprocaine and lidocaine
·1. Mainly used for infiltration anesthesia.
·2. For the lower abdomen takes a long time surgery. Can also be used for local anesthesia of the limbs.
·3. For "closed therapy", the treatment of certain injuries and inflammation, can damage, inflammation of the symptoms of some relief.
·4. To correct limb vasomotor dysfunction.
·5. treatment of neurosis
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