Wuhan Yuancheng Gongchuang Technology Co., Ltd.

Dutasteride, Propecia, CAS: 164656-23-9 manufacturer / supplier in China, offering Highest Quality 99% Purity Dutasteride Avodart Raw Powder CAS: 164656-23-9, Adrenalone Hydrochloride, Dl-Adrenalin, Epinephrine Bitartrate, Isoprenaline Hydrochloride, 99% Purity Estradiol with Safe Shipping and so on.

Supplier Homepage Product List Anti-Estrogens & PCT Powders Highest Quality 99% Purity Dutasteride Avodart Raw Powder CAS: 164656-23-9

Highest Quality 99% Purity Dutasteride Avodart Raw Powder CAS: 164656-23-9

FOB Price:US $8.3 - 18 / g
Purchase Qty. (g) FOB Price
50-99 US $18 / g
100-299 US $12 / g
300-499 US $9.5 / g
500-999 US $8.876 / g
1,000+ US $8.3 / g
Get Latest Price
Min. Order: 50 g
Production Capacity: 100kg/Month
Transport Package: Safe and Discreet Packing
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

Basic Info.

Model NO.:CAS: 164656-23-9
Powder:Yes
Customized:Non-Customized
Certification:ISO 9001
Suitable for:Adult
State:Solid
Purity:>99%
Name:Dutasteride
Synonym:Avodart
CAS:164656-23-9
M.F.:C27h30f6n2o2
M.W.:528.53
Assay:99%
Appearance:White Powder
Payment Method:Bank Transfer, Western Union, Money Gram, Bitcoin
Shipping Method:EMS, DHL, TNT, UPS, FedEx, by Sea, by Air
Usage:Used in The Treatment of Benign Prostatic Hyperpla
Trademark:WHYCG
Specification:99%
Origin:China
HS Code:2942000000

Product Description

Dutasteride
product Name: Dutasteride
Synonyms: (5alpha,17beta)-n-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide;Avodart
CAS Registry Number: 164656-23-9
Assays: 99%
Packaging: 1kg/Aluminum tin
Molecular Formula: C27H30F6N2O2 
Molecular Weight: 528.53
Appearance: White or white crystalline powder
Usage: Pharmaceutical Intermediates
 
Product Name:Dutasteride
Synonyms:(5alpha,17beta)-n-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide;DUTASTERIDE;GG-745, GI-198745,;5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4- Aza -androst-1-ene-17-carboxamide;Duagen;(5a,17)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide;Avodart;GI 198745
CAS:164656-23-9
MF:C27H30F6N2O2
MW:528.53
EINECS: 
Product Categories:Miscellaneous Biochemicals;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone;Hormone Drugs;API
Mol File:164656-23-9.mol
 
 
Dutasteride Chemical Properties
mp 242-250°C
storage temp. -20°C Freezer
 
Safety Information
 
MSDS Information
 
Dutasteride Usage And Synthesis
Medicines to treat benign prostatic hyperplasiaOn October 9, 2002, dutasteride that was developed by GSK was approved by the US Food and Drug Administration for the use in the treatment of prostate enlargement. 
On June 19, 2008, GSK announced that the FDA approved for the combination of idutasteride and tamsulosin in the treatment of prostate hyperplasia.
In China, on of two elderly men over the age of 60 have benign prostatic hyperplasia. It can cause urinary tract symptoms, including significant rise in frequency of urination, thin urine flow, bladder emptying difficulties, as well as nocturia. It even can cause serious complications, like acute urinary retention, reduce the patients' life quality, and affect their social life.
Dutasteride is the first and the only dual 5α reductase inhibitor to be used in the treatment of prostatic hyperplasia. It can improve urinary system symptom, reduce the onset of acute urinary retention and the risk of prostate surgery. Tamsulosin is α receptor blockers. It can improve the symptom of prostate hyperplasia.
The human body has both type I reductase and type II 5α reductase. Type II mainly exists in the prostate. And type I mainly distributes in the liver and skin. 5α Reductase is the important reason that leads benign hyperplastic prostate disease continuous developing. It can make testosterone in patients' prostate transform to DHT with stronger activity, which can cause prostate cells hyperplasia and prostate hypertrophy. Therefore, the inhibition of 5α reductase is the key to treat benign prostatic hyperplasia. And dutasteride can inhibit the type I and type II 5α reductase at the same time. Through this double inhibition mechanism, dutasteride can rapidly and continuously decrease prostate volume, significantly improve the urinary symptoms, reduce the risk of acute urinary retention and related prostate surgery, and bring benefit to patients with persistent, especially the middle and severe patients with benign prostatic hyperplasia.
The above information is edited by the Chemicalbook Geqian.
Clinical evaluationThe approval of the US Food and Drug Administration bases on a multicenter randomized double-blind controlled clinical study for two years -- the first long-term evaluation of the combination of dutasteride and alpha blockers in clinical research. The patients include moderate and severe prostate hyperplasia patients (age is greater than or equal to 50, prostatic volume (PV) ≥ 30cc, serum prostate specific antigen (PSA) level is 1.5 ~ 10 ng/mL, 5 mL/s < maximum urinary flow rate (Qmax) ≤15 mL/s, the minimum urine output ≥ 125 mL, the international prostate symptom score (IPSS) ≥ 12). Patients firstly take placebo for four weeks, and then randomly take both dutasteride 0.5 mg/day and tamsulosin 0.4 mg/day, or only take dutasteride 0.5 mg/day, tamsulosin 0.4 mg/day.
The clinical study shows that the treatment effect of the combination of dutasteride is better than single treatment after twelve and twenty-four months. The most common adverse reactions of this product are impotence, decreased libido, breast disease (including breast augmentation, swelling), ejaculatory dysfunction, and dizziness.
ApplicationDutasteride is 5α reductase inhibitor.
Chemical PropertiesWhite Crystalline Solid
UsageUsed in the treatment of benign prostatic hyperplasia. Dual inhibitor of 5a-reductase isoenzymes type 1 and 2; structurally related to Finasteride.
UsageUsed in the treatment of benign prostatic hyperplasia. Dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride.
Usageantihypertensive, ACE inhiibitor
UsageDutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.

Packaging & Delivery Process:
 
1.  Mass stock, to make sure delivery promptly at the every day when the payment is done.
2.  Having been engaged in this field for years, we have sophisticated and professional logistic agent, which can guarantee safe and speedy delivery.
3.   Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 2 mgial to 20mgial at one time to your destination.
4.  Packing pictures and tacking code are provided within 12 hours as soon as receiving the payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.
5.   Perfect after-sale service: Any questions or problems after receiving the product happend, please feel free to contact us. Problems would be solved immediately.


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