White Crystalline Opical Anesthesia Powder Benzocaine
Other name: Anesthesin Aethoform Ethyl 4-Aminobenzoate
CAS No: 94-09-7
Molecular formula: C9H11NO2
Molecular weight: 165.19
Appearance: White crystalline powder
Usage: It is a topical anesthetic that helps to numb the pain and itching for wounds, pain, ulcer and hemorrhoids, as well as intermediates of cough suppressants.
Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is also combined with antipyrine to form A/B otic drops to relieve ear pain and remove earwax.
Benzocaine is a widely used local anesthetic. Unlike a general anesthetic that effects the entire body, a local anesthetic desensitizes a specific area of the body. The drug is frequently used in a range of externally applied, over-the-counter products used to numb different areas of the body. It functions by obstructing the entrance of sodium into nerve endings, halting the sensation of pain.
Local anesthetic has a variety of uses, but chief among them is its use in non-prescription medications and ointments that help decrease minor pain. People apply the over-the-counter remedies directly to various body surfaces, such as irritated or sunburned skin. Oral uses are also common and can be helpful for mouth or teeth pain. Some people use the medication as a treatment for hemorrhoids or to relieve rectal and vaginal discomfort. Medical offices and hospitals also utilize benzocaine during procedures that require the insertion of a medical instrument into the body.
Benzocaine can be used as the raw materials of Otho imitation, Orthocaine and Procaine; At the same time, it is used as a topical anesthetics in medicine with analgesic, antipruritic effect, mainly used for wounds, ulcers, mucosal surface anesthesia plane and hemorrhoids pain and itching. Its ointment can also be used as the lubrication of nasopharyngeal catheter, sudden pain within the endoscope mirror etc...To relief the pain and discomfort of skin itching such as minor burns, sunburn, trauma and insect bites. Ear preparation is used to reduce acute congestive, concentrated otitis externa, swimming otitis pain and itching and external ear. It is also effective for toothache, sore throat, oral ulcer, hemorrhoids, anal fissure, pruritus vulvae. Benzocaine can be usded as male genital desensitizer to make ejaculation slow or anesthesia lubricant of endoscopic tube and catheter.
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neuron, causing depolarization of the nerve and subsequent initiation of an action potential. The action potential is propagated down the nerve toward the central nervous system, which interprets this as pain. Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the nerve membrane, stopping the propagation of the action potential.
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|Appearance||White crystalline powder|
|Assay||99.0% to 101.0%||99.5%|
|Melting point||89°C to 92°C||89°C to 90.5°C|
|Loss on drying||0.5%Max.||0.22%|